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Michael J. describes a punk by vampire weekend Fox Foundation goth weekend recalls Awards $2.9 Million for Two New Parkinson's DiseaseClinical TrialsNEW YORK, Jan 12 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation forParkinson's Research awarded about $2.9 million total for two clinical studiesthat will test drugs already approved in other disease indications forpotential efficacy against Parkinson's disease. Because both drugs beingtested are already known to be safe for humans, they hold potential to moveswiftly toward regulatory approval for use in Parkinson's patients if theyprove effective in PD.One funded team will investigate the potential of simvastatin (marketed underthe trade name Zocor), a drug currently used to treat high cholesterol, toreduce dyskinesias -- the disruptive, uncontrollable movements that are a sideeffect of long-term dopamine replacement. The other team will undertake aPhase 2 study to determine whether isradipine (marketed under the trade nameDynacirc), an approved high blood pressure medication, can rescue dopamineneurons from the degeneration seen in Parkinson's.Although the drugs' current uses for cholesterol and blood pressure managementmight not seem relevant for PD, researchers found that the mechanisms by whicheach drug acts had unintended but beneficial effects on Parkinson's diseasepathways in preclinical models of the disease. The funding was awarded under the Foundation's Clinical Intervention Awardsinitiative, one of MJFF's three annually recurring Edmond J Safra CorePrograms for PD Research.

The program supports novel or critical clinicalintervention trials of promising therapeutic approaches that can significantlyand fundamentally improve treatments for Parkinson's disease.Funded projects are listed below a vampire weekend . Detailed information, including grantabstracts and researcher bios, is available at Randomized, Placebo-controlled, Multiple Crossover (n-of-1), Pilot trial ofSimvastatin on the Treatment of Levodopa-induced Dyskinesia in Parkinson'sDisease PatientsErwan Bezard, PhD, Universiy of Bordeaux, France, and Francois Tison, MD, PhD,Head of Movement Disorder Unit, University Hospital of Bordeaux, FranceA Pilot Phase II Double-Blind, Placebo-Controlled, Dosage Finding andTolerability Study of Isradipine as a Disease Modifying Agent in Patients withEarly Parkinson's DiseaseTanya Simuni, MD, Parkinson's Disease and Movement Disorders Center,Northwestern UniversityAbout The Michael J Fox Foundation Founded in 2000, The Michael J gothic weekend . Fox Foundation for Parkinson's Research isdedicated to ensuring the development of a cure for Parkinson's disease withinthe decade through an aggressively funded research agenda vampire subcultures . The Foundation hasfunded $135 million in research to date.SOURCEMichael J goth weekend . Fox FoundationMedia: Holly Barkhymer, +1-212-509-0995 x242, ,Research: Brian Fiske, PhD, +1-212-509-0995 x203, , bothof Michael J Fox Foundation. NEW YORK--(Business Wire)--Marsh & McLennan Companies, Inc. (MMC) today published Volume 1, 2009 ofViewpoint, the journal that highlights the firm`s latest thinking on today`scritical issues and risks.

The new issue is available for download on mmc and contains the following articles:* Risk Governance: Seeing the Forest for the Trees - A look into the reasons whyrisk management failed so many institutions so spectacularly and led, in part,to the financial crisis . Written by Andrew Kuritzkes, a partner and seniormember of Oliver Wyman`s Finance and Risk practice, the article goes on todiscuss what organizations can do to avoid making the same mistakes gothic weekend . * Leading Through a Crisis: Getting Back to Basics - With the current financialcrisis as a backdrop, Mark Nadler and Janet Spencer of Oliver Wyman`s DeltaOrganization & Leadership business discuss the guiding principles needed for topleaders to steer their organizations through the toughest of times vampire subcultures . * Food-Safety Strategies: How to Protect Your Company and Your Consumers - Giventhe unprecedented number offood-borne illness (in the United States alone thereare an estimated 76 million illnesses and 5,000 deaths annually) organizationsneed to be proactive and have demonstrable systems in place to protect theirconsumers by managing food-safety risks across their supply chain . In thisarticle, Melissa Hersh and Hester Shaw of Marsh Risk Consulting explore thesteps companies can take to protect themselves and their consumers. * Healthcare Planning for an Aging World - Christine Owen of Mercer`s GlobalHealth Management Consulting practice takes a close look at the World EconomicForum report The Future of Pensions and Healthcare in a Rapidly Ageing World:Scenarios to 2030, which indicates that new forms of collaboration between keystakeholders - individuals, financial institutions, healthcare providers,employers, and governments - will be critical in order to finance the ongoingwell-being of current and future generations in a sustainable manner. * The Continuing Evolution of Risk Modeling - Ryan Ogaard, Global Head of GuyCarpenter`s Instrat Unit, discusses the expertise, technology, and bestpractices that have evolved to help firms overcome the inertia that has keptthem from implementing a holistic risk management framework.MMC is a global professional services firm providing advice and solutions in theareas of risk, strategy and human capital.